thioredoxin reductase

Thioredoxin system is comprised of thioredoxin, thioredoxin reductase and NADPH, playing multiple biological functions, such as anti-oxidation, anti-apoptosis and promoting cell proliferation.

硫氧还蛋白、硫氧还蛋白还原酶和NADPH组成硫氧还蛋白系统发挥着抗氧化，抗凋亡及促进细胞增殖等作用。

Competitive Quantitative RT-PCR Analysis of the Expression of Thioredoxin Reductase in HUVECs Exposed on Serum from PIH

竞争性定量RT-PCR检测妊高征患者血清对脐静脉内皮细胞TR基因表达的影响

Effect of selenium deficiency on activity and expression of mitochondrial thioredoxin reductase of rat myocardium

低硒大鼠心肌线粒体型硫氧还蛋白还原酶的活性和表达

Objective To study the changes of activity and expression of mitochondrial thioredoxin reductase ( TR2) in activity and possible mechanism.

目的探讨低硒状态下大鼠心肌线粒体型硫氧还蛋白还原酶（TR2）的活性和表达变化，分析体内硒水平改变对TR2活性的影响及其可能的机制。

Methods Wistar rats were fed on selenium-deficient diets for 14 weeks. The changes of thioredoxin reductase activity, protein expression and gene expression were detected by biochemical methods, Western blot and Northern blot.

方法用低硒饲料喂养断乳2周的Wistar大鼠14周，分别采用生物化学方法、western blot和Northern Blot杂交检测心肌组织中TR的活性改变及TR蛋白、基因表达变化。

Spectroscopy Study on Thioredoxin Reductase From Human Brain Objective: To clone thioredoxin reductase ( TR) gene and express in E. coli.

人脑硫氧还蛋白还原酶的光谱学研究目的：克隆人硫氧还蛋白还原酶（TR）基因并构建原核表达载体，获得TR蛋白。

Objective To study the expression and role of thioredoxin reductase ( TR) in spinal cord injury model in rats.

目的：探讨大鼠脊髓损伤模型中硫氧还蛋白还原酶（Thioredoxin reductase，TR）的动态表达及其作用。

Moreover, other selenoproteins ( e.g. selenoprotein P and thioredoxin reductase) also have been shown to possess antioxidant properties.

其它含硒蛋白（如硒蛋白P和硫氧还蛋白还原酶）也具有抗氧化特性。

Cloning of Human Thioredoxin Reductase cDNA and Its Expression in E. coli

人硫氧还蛋白还原酶cDNA的克隆及在大肠杆菌中的表达

Study of relationship between cardiomyocytes injury induced by selenium-deficiency and thioredoxin reductase

低硒心肌损伤与硫氧还蛋白还原酶的关系研究

Objective: To clone the thioredoxin reductase ( TR) gene from human fatal brain.

目的：从人脑组织中克隆硫氧还蛋白还原酶基因。

Thioredoxin reductase gene fragments in porcine brain: sequence study

猪脑硫氧还蛋白还原酶基因片断的序列分析

Effects of Scutellarin on glutathione peroxidase and thioredoxin reductase gene expression and activities in rats supplemented with upper limit Selenium

灯盏花素对UL补硒大鼠谷胱甘肽过氧化物酶和硫氧还蛋白还原酶基因表达和活性的影响

Expression and role of thioredoxin reductase in spinal cord injury model in rats

大鼠脊髓损伤模型中硫氧还蛋白还原酶的表达及其作用

Objective The present study aimed at investigating the influences of exercise on thioredoxin reductase ( TR) of myocardium and skeletal muscle in rats.

目的：观察运动对大鼠心肌、骨骼肌硫氧还蛋白还原酶（TR）的影响。

Expression of thioredoxin reductase in hippocampus of Alzheimer ′ s disease model in rats

硫氧还蛋白还原酶在大鼠阿尔茨海默病模型海马结构中的表达

The Experimental Study of the Treatment of Non-alcoholic Fatty Liver Disease Through Thioredoxin Reductase Up-regulated

硫氧还蛋白还原酶表达上调治疗非酒精性脂肪性肝病的实验研究

Results The expressions of the protein and gene of mitochondrial thioredoxin reductase in stress group were higher than those of control group.

结果应激组大鼠心肌中线粒体型硫氧还蛋白还原酶基因和蛋白表达均高于非应激组。

Cloning and sequencing of human brain thioredoxin reductase

人脑硫氧还蛋白还原酶基因的克隆及测序

The Influences of Endurance Training and Single Bout of Exhaustive Exercise on Thioredoxin Reductase of Myocardium and Skeletal Muscle in Rats

耐力训练和一次性力竭运动对大鼠心肌和骨骼肌硫氧还蛋白还原酶的影响

Induced Drug Resistance and Explored the Changes of the Activity of Thioredoxin Reductase in Pancreatic Cancer Cell Line

吉西他滨诱导胰腺癌细胞株SW1990的耐药作用与硫氧还蛋白还原酶活性改变的观察

Conclusions Selenium deficiency decreases activity and protein levels of thioredoxin reductase in cardiomyocytes.

结论低硒能够降低心肌TR的活性和蛋白表达水平，但并不影响此酶的基因表达。

In this study, the bioavailability of Nano-Se and SeMet was compared, and it was found that, as compared with SeMet, Nano-Se possesses equal efficacy in increasing the activities of glutathione peroxidase and thioredoxin reductase.

本研究进一步比较了纳米硒与硒蛋氨酸的生物利用。研究结果显示，与硒蛋氨酸相比，纳米硒具有相等的效能提高各组织谷胱甘肽过氧化物酶和硫氧还蛋白还原酶的活力。

Objective To establish gemcitabine-resistant pancreatic cancer cell strain and study the role of thioredoxin reductase ( TrxR) in drug-resistant process.

目的建立对吉西他宾耐药的胰腺癌细胞株，探讨硫氧还蛋白还原酶（TrxR）在耐药过程中的作用。

Conclusions The increased expression of mitochondria thioredoxin reductase may protect the heart against oxidative stress injury.

结论线粒体型硫氧还蛋白还原酶基因和蛋白表达的增加有利于大鼠心肌抗氧化损伤。